TVB provides a generic framework for computational modeling and tools to extract structural and functional connectomes from multimodal datasets ( Schirner et al., 2015) in order to link personalized brain network structure with neural population models.
The Virtual Brain (TVB ) is a Python-based neuroinformatics platform for the simulation of realistic large-scale networks ( Jirsa et al., 2010) of neural population models available for all major operating systems, including Windows, Mac OS, and Linux ( Ritter et al., 2013 Sanz-Leon et al., 2013 Roy et al., 2014 Woodman et al., 2014). TVB-EduPack can be obtained as part of TVB from. Like TVB, EduPack is an open source community project that lives from the participation and contribution of its users. This article covers the implementation of TVB-EduPack and its integration into TVB architecture.
EduPack offers two educational functionalities that seamlessly integrate into TVB's graphical user interface (GUI): (i) interactive tutorials introduce GUI elements, guide through the basic mechanics of software usage and develop complex use-case scenarios animations, videos and textual descriptions transport essential principles of computational neuroscience and brain modeling (ii) an automatic script generator records model parameters and produces input files for TVB's Python programming interface thereby, simulation configurations can be exported as scripts that allow flexible customization of the modeling process and self-defined batch- and post-processing applications while benefitting from the full power of the Python language and its toolboxes. To enable researchers from various backgrounds a quick start into TVB and brain network modeling in general, we developed an educational module: TVB-EduPack. TVB is equipped with a graphical and a command-line interface to create models that capture the characteristic biological variability to predict the brain activity of individual subjects. The framework addresses clinical and neuroscientific questions by simulating multi-scale neural dynamics that range from local population activity to large-scale brain function and related macroscopic signals like electroencephalography and functional magnetic resonance imaging. The Virtual Brain (TVB ) is a neuroinformatics platform for full brain network simulation based on individual anatomical connectivity data.
4Intelligent Systems and Robotics Lab, Department of Mathematics and Computer Science, Free University, Berlin, Germany.3Bernstein Focus State Dependencies of Learning and Bernstein Center for Computational Neuroscience, Berlin, Germany.2Department of Neurology, Charité – University Medicine, Berlin, Germany.1Minerva Research Group BrainModes, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Jirsa 8, Anthony Randal McIntosh 9 and Petra Ritter 1,2,3,10 * Henrik Matzke 1,2,3†, Michael Schirner 2,3†, Daniel Vollbrecht 2,3, Simon Rothmeier 1,2,3, Adalberto Llarena 2,3,4, Raúl Rojas 4, Paul Triebkorn 2, Lia Domide 5, Jochen Mersmann 6, Ana Solodkin 7, Viktor K.